Antibacterial potential of celery leaf extract toothpaste on the growth of Streptococcus mutans ATCC 25175

ABSTRACTIntroduction: Celery (Apium graveolens L.) is a member of the Apiaceae family that can grow everywhere. contains flavonoids, saponins, tannins, essential oils, apigenin, choline, vitamins A, B, C, asparagine bitter substances. and tannins which are antibacterial compounds. Streptococcus mutans Gram-positive bacterium creating an acidic atmosphere in oral cavity, causes insufficient saliva to prevent enamel demineralisation lead dental caries. The purpose this study was analyze inhibition effect celery leaf extract on growth mutans. Methods: This type experimental laboratory research uses Post Test Only Control Group Design. samples were Apium L. ATCC 25175. number treatment groups 24 with concentrations 20, 40, 60, 80%. Toothpaste containing ingredients used as positive control for negative control, basic toothpaste formula without ingredients, namely carboxymethyl cellulose (CMC), xylitol, calcium carbonate (CaCO3), sorbitol, sodium lauryl sulphate (SLS), natrium benzoate. Data analysis using one-way ANOVA test normality Shapiro-Wilk homogeneity Levene test. results at concentration 60 80% there no significant difference because sig value >0.05. Results: showed inhibits (p <0.05) Conclusion: There mutans.Keywords: streptococcus 25175, inhibition, toothpaste, celery, apium L